Aminoimidazolaza
(Preusmjereno sa stranice `)
Aminoimidazolaza (EC 3.5.4.8) je enzim sa sistematskim imenom 4-aminoimidazol aminohidrolaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Aminoimidazolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.4.8 | ||||||||
| CAS broj | 9025-17-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 4-aminoimidazol + H2O imidazol-4-on + NH3
Za dejstvo ovog enzima je neophodan jon Fe2+.
Reference uredi
- ↑ Rabinowitz, J.C. and Pricer, W.E. (1956). „Purine fermentation by Clostridium cylindrosporum. V. Formiminoglycine”. J. Biol. Chem. 222: 537-554. PMID 13367024.
- ↑ Freter, K., Rabinowitz, J.C. and Witkop, B. (1957). „Labile Stoffwechselprodukte. V. Zur Biogenese des Formiminoglycins aus 4(5H)-imidazolon”. Ann. Chem. 607: 174-187.
- ↑ Vogels, G.D. and Van der Drift, C. (1976). „Degradation of purines and pyrimidines by microorganisms”. Bacteriol. Rev. 40: 403-468. PMID 786256.
- ↑ DeMoll, E. and Auffenberg, T. (1993). „Purine metabolism in Methanococcus vannielii”. J. Bacteriol. 175: 5754-5761. PMID 8376322.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.