Tuberoinfundibularni put

Tuberoinfundibularni put je populacija dopaminskih neurona u arkuatnom jezgru (lat. nucleus arcuatus hypothalami) mezokortikalnog hipotalamusa ('tuberalni region') koji formiraju projekciju na infundibularni region (lat. eminentia mediana hypothalami). To je jedan od četiri glavna dopaminska puta u mozgu. Oslobađanje dopamina na tom mestu reguliše izlučivanje prolaktina iz prednje hipofizne žlezde.^[1]^[2]

Neki antipsihotički lekovi blokiraju dopamin u tuberoinfundibularnom putu, što može da uzrokuje povišenje nivoa prolaktina u krvi (hiperprolaktinemia). Moguće posledice su abnormalna laktacija^[3], poremećaji menstrualnog ciklusa, problemi vida, glavobolja i seksualna disfunkcija.

Drugi dopaminski putevi uredi

Drugi glavni dopaminski putevi su:

Vidi još uredi

Literatura uredi

↑ Goldman, Howard H (2000). Review of general psychiatry. New York: Lange Medical Books/McGraw-Hill, Medical Pub. Division. ISBN 0-8385-8434-9.
↑ Rippe, James M.; Irwin, Richard S. (2008). Irwin and Rippe's intensive care medicine. Philadelphia: Wolters Kluwer Health / Lippincott Williams & Wilkins. ISBN 0-7817-9153-7.
↑ Hooper JH, Welch VC, Shackelford RT (November 1961). „Abnormal lactation associated with tranquilizing drug therapy”. JAMA : the Journal of the American Medical Association 178: 506–7. PMID 14448766.

Spoljašnje veze uredi

NeuroNames ancil-745
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[isbn0-8385-8434-9-1] Goldman, Howard H (2000). Review of general psychiatry. New York: Lange Medical Books/McGraw-Hill, Medical Pub. Division. ISBN 0-8385-8434-9.

[isbn0-7817-9153-7-2] Rippe, James M.; Irwin, Richard S. (2008). Irwin and Rippe's intensive care medicine. Philadelphia: Wolters Kluwer Health / Lippincott Williams & Wilkins. ISBN 0-7817-9153-7.

[pmid14448766-3] Hooper JH, Welch VC, Shackelford RT (November 1961). „Abnormal lactation associated with tranquilizing drug therapy”. JAMA : the Journal of the American Medical Association 178: 506–7. PMID 14448766.

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