Trimazosin

Trimazosin
(IUPAC) ime
	(2-hidroksi-2-metilpropil) 4-(4-amino-6,7,8-trimetoksihinazolin-2-il)piperazin-1-karboksilat
Klinički podaci
Identifikatori
CAS broj	53746-46-6
ATC kod	C02CA03
PubChem	37264
UNII	31L760807H
ChEMBL	CHEMBL513301
Hemijski podaci
Formula	C20H29N5O6
Mol. masa	435,47 g/mol
InChI
	InChI=1S/C20H29N5O6/c1-20(2,27)11-31-19(26)25-8-6-24(7-9-25)18-22-14-12(17(21)23-18)10-13(28-3)15(29-4)16(14)30-5/h10,27H,6-9,11H2,1-5H3,(H2,21,22,23) ; Key: YNZXWQJZEDLQEG-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

Trimazosin je simpatomimetički lek. On je alfa blokator.^[4]

Završni stupanj sinteze trimazosina je^[5]

Reference uredi

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ van Kalken CK, van der Meulen J, Oe PL, Vriesendorp R, Donker AJ (1986). „Pharmacokinetics of trimazosin and its effects on blood pressure, renal function and proteinuria during short-term therapy of patients with impaired renal function and hypertension”. Eur. J. Clin. Pharmacol. 31 (1): 63–8. DOI:10.1007/BF00870988. PMID 3780829.
↑ Hess, H. J.; 1972, U.S. Patent 3,669,968

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