T-1824

T-1824
	tetranatrijum (6E,6'E)-6,6-[(3,3'-dimetilbifenil-4,4'-diil)di(1E)hidrazin-2-il-1-iliden]bis(4-amino-5-okso-5,6-dihidronaftalen-1,3-disulfonat)
Identifikacija
CAS registarski broj	314-13-6
PubChem	6321418
KEGG	C19422
MeSH	Evans+blue
ChEMBL	CHEMBL1200712
Jmol-3D slike	Slika 1
SMILES
	[Na+].[Na+].[Na+].[Na+].[O-]S(=O)(=O)c6cc(c(N)c5c6C=C/C(=N\Nc1ccc(cc1C)c4ccc(N\N=C3/C=Cc2c(cc(c(N)c2C3=O)S([O-])(=O)=O)S([O-])(=O)=O)c(C)c4)C5=O)S([O-])(=O)=O
Svojstva
Molekulska formula	C34H24N6Na4O14S4
Molarna masa	960.81 g mol−1
	(šta je ovo?) (verifikuj) ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

T-1824 (Evansovo plavo) je azo boja koja ima veoma visok afinitet za serumski albumin. Zbog toga je koristan u fiziologiji u procenjivanju proporcije telesne vode sadržane u krvnoj plazmi.^[5]

Evansovo plavo se koristi u testu vitalnosti zbog sposobnosti penetracije u nevitalne ćelije. Ovaj metod je podložan pravljenju greška jer oštećene ćelije mogu da imaju sposobnost popravke.^[6]

Reference uredi

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Medicinski koledž Džordžija, 7/7ch02/7ch02p17
↑ Crutchfield A, Diller K, Brand J (1999). „Cryopreservation of Chlamydomonas reinhardtii (Chloropkhyta)” (HTML). European Journal of Phycology 34 (1): 43–52. DOI:10.1080/09670269910001736072.

Spoljašnje veze uredi

Portal Hemija

el-Sayed H, Goodall S, Hainsworth R (1995). „Re-evaluation of Evans blue dye dilution method of plasma volume measurement”. Clin Lab Haematol 17 (2): 189–94. PMID 8536425.

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.

[4] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit

[5] Medicinski koledž Džordžija, 7/7ch02/7ch02p17

[6] Crutchfield A, Diller K, Brand J (1999). „Cryopreservation of Chlamydomonas reinhardtii (Chloropkhyta)” (HTML). European Journal of Phycology 34 (1): 43–52. DOI:10.1080/09670269910001736072.

[5]

[1]

[2]

[3]

[4]

[6]