Sukcinimid

Sukcinimid
	Pirolidin-2,5-dion
Drugi nazivi	Sukcinimid; Imid sukcinske kiseline
Identifikacija
CAS registarski broj	123-56-8
PubChem	11439
ChemSpider	10955
UNII	10X90O3503
ChEBI	9307
ChEMBL	CHEMBL275661
RTECS registarski broj toksičnosti	WN2200000
ATC code	G04BX10
Jmol-3D slike	Slika 1
SMILES
	O=C1NC(=O)CC1
InChI
	InChI=1S/C4H5NO2/c6-3-1-2-4(7)5-3/h1-2H2,(H,5,6,7) ; Kod: KZNICNPSHKQLFF-UHFFFAOYSA-N InChI=1/C4H5NO2/c6-3-1-2-4(7)5-3/h1-2H2,(H,5,6,7); Kod: KZNICNPSHKQLFF-UHFFFAOYAV
Svojstva
Molekulska formula	C4H5NO2
Molarna masa	99.09 g mol−1
Agregatno stanje	Beli kristalni prah
Gustina	1,41 g/cm3
Tačka topljenja	125-127 °C, 398-400 K, 257-261 °F
Tačka ključanja	287-289 °C, 560-562 K, 549-552 °F
Rastvorljivost u vodi	1 g/3 mL
pKa	9,5
Opasnost
Podaci o bezbednosti prilikom rukovanja (MSDS)	External MSDS
Opasnost u toku rada	Iritant; blago zapaljiv
R i S oznake	S24/25 S28 S37 S45
LD50	14 g/kg (pacov, oralno)
Srodna jedinjenja
Srodna Imidi	Maleimid, N-hlorosukcinimid, N-bromosukcinimid
	(šta je ovo?) (verifikuj) ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

Sukcinimid je ciklični imid sa formulom C₄H₅NO₂. On se koristi u mnoštvu organskih sinteza, kao i u industrjskim procesima posrebravanja.^[6]^[7]

Sukcinimidi uredi

Sukcinimidi su jedinjenja koja sadrže sukcinimidnu grupu. Ta jedinjenja imaju široku primenu. Neki od njih se koriste kao antikonvulsanti, uključujući etosuksimid, fensuksimid, i mesuksimid. Sukcinimidi se takođe koriste za formiranje kovalentnih veza između proteina ili peptida i plastike, što je korisno u mnoštvu tehnika za testiranje.

Reference uredi

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Susan Budavari, ur. (1996). The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals (12th izd.). Merck. str. 9040. ISBN 0-911910-12-3.
↑ Clayden Jonathan, Nick Greeves, Stuart Warren, Peter Wothers (2001). Organic chemistry. Oxford, Oxfordshire: Oxford University Press. ISBN 0-19-850346-6.
↑ Smith, Michael B.; March, Jerry (2007). Advanced Organic Chemistry: Reactions, Mechanisms, and Structure (6th izd.). New York: Wiley-Interscience. ISBN 0-471-72091-7.

Vidi još uredi

Sukcinski anhidrid

Spoljašnje veze uredi

Portal Hemija

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[4] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit

[Merck-5] Susan Budavari, ur. (1996). The Merck Index: An Encyclopedia of Chemicals, Drugs, and Biologicals (12th izd.). Merck. str. 9040. ISBN 0-911910-12-3.

[Clayden1st-6] Clayden Jonathan, Nick Greeves, Stuart Warren, Peter Wothers (2001). Organic chemistry. Oxford, Oxfordshire: Oxford University Press. ISBN 0-19-850346-6.

[March6th-7] Smith, Michael B.; March, Jerry (2007). Advanced Organic Chemistry: Reactions, Mechanisms, and Structure (6th izd.). New York: Wiley-Interscience. ISBN 0-471-72091-7.

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