Sukcinat dehidrogenaza
Sukcinat dehidrogenaza (EC 1.3.99.1, sukcinski dehidrogenaza, fumaratna reduktaza, fumarinska hidrogenaza, sukcinodehidrogenaza, dehidrogenaza sukcinske kiseline, sukcinatna oksidoreduktaza, sukcinilna dehidrogenaza, sukcinat:(akceptor) oksidoreduktaza) je enzim sa sistematskim imenom sukcinat:akceptor oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju:
| Sukcinat dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.3.99.1 | ||||||||
| CAS broj | 2593986 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ovaj flavoprotein (FAD) sadrži gvožđe-sumporne centre. On je komponenta enzima EC 1.3.5.1, sukcinatne dehidrogenaze (ubihinon).
Reference
uredi- ↑ Hatefi, Y., Ragan, C.I. and Galante, Y.M. (1985). „The enzymes and the enzyme complexes of the mitochondrial oxidative phosphorylation system”. u: Martonosi, A.. The Enzymes of Biological Membranes. 4 (2nd izd.). New York: Plenum Press. str. 1-70.
- ↑ Singer, T.P. and Kearney, E.B. (1963). „Succinate dehydrogenase”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 7 (2nd izd.). New York: Academic Press. str. 383-445.
- ↑ Singer, T.P., Kearney, E.B. and Bernath, P. (1956). „Studies of succinic dehydrogenase. II. Isolation and properties of the dehydrogenase from beef heart”. J. Biol. Chem. 223: 599-613. PMID 13385208.
- ↑ Warringa, M.G.P.J. and Giuditta, A. (1958). „Studies on succinic dehydrogenase. IX. Characterization of the enzyme from Micrococcus lactilyticus”. J. Biol. Chem. 230: 111-123. PMID 13502379.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.