Proteinska disulfid-izomeraza
(Preusmjereno sa stranice Protein disulfid izomeraza)
Proteinska disulfid-izomeraza (EC 5.3.4.1, Protein disulfide-isomerase) je enzim sa sistematskim imenom protein disulfid-izomeraza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Proteinska disulfid-izomeraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 5.3.4.1 | ||||||||
| CAS broj | 37318-49-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- katalizuje preuređivanje -S-S- veza proteina
Za dejstvo ovog enzima je neophodan redukujući agens.
Reference uredi
- ↑ De Lorenzo, F., Goldberger, R.F., Steers, E., Givol, D. and Anfinsen, C.B. (1966). „Purification and properties of an enzyme from beef liver which catalyzes sulfhydryl-disulfide interchange in proteins”. J. Biol. Chem. 241: 1562-1567. PMID 5946614.
- ↑ Fuchs, S., De Lorenzo, F. and Anfinsen, C.B. (1967). „Studies on the mechanism of the enzymic catalysis of disulfide interchange in proteins”. J. Biol. Chem. 242: 398-402. PMID 6022836.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.