Prekorin-4 C11-metiltransferaza
Prekorin-4 C11-metiltransferaza (EC 2.1.1.133, prekorin-3 metilaza, CobM) je enzim sa sistematskim imenom S-adenozil-L-metionin:prekorin-4 C11 metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
Prekorin-4 C11-metiltransferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.1.1.133 | ||||||||
CAS broj | 152787-65-0 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- S-adenozil-L-metionin + prekorin-4 S-adenozil-L-homocistein + prekorin-5
Ovaj enzim učestvuje u aerobnom kobalaminskom biositetičkom putu.
Reference uredi
- ↑ Crouzet, J., Cameron, B., Cauchois, L., Rigault, S., Rouyez, M.C., Blanche, F. (1990). „, Thibaut D., Debussche, L. Genetic and sequence analysis of an 8.7-kilobase Pseudomonas denitrificans fragment carrying eight genes involved in transformation of precorrin-2 to cobyrinic acid”. J. Bacteriol. 172: 5980-5990. PMID 2211521.
- ↑ Roth, J.R., Lawrence, J.G., Rubenfield, M., Kieffer-Higgins, S., Church, G.M. (1993). „Characterization of the cobalamin (vitamin B12) biosynthetic genes of Salmonella typhimurium”. J. Bacteriol. 175: 3303-3316. PMID 8501034.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.