Glukokinaza
Glukokinaza (EC 2.7.1.2, glukokinaza (fosforilacija)) je enzim sa sistematskim imenom ATP:D-glukoza 6-fosfotransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Glukokinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| Identifikatori | |||||||||
| EC broj | 2.7.1.2 | ||||||||
| CAS broj | 9001-36-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- ATP + D-glukoza ADP + D-glukoza 6-fosfat
Ova grupa enzima je prisutna kod bezkičmenjaka i mikroorganizama koji su visoko specifični za glukozu.
Reference uredi
- ↑ Baumann, P. (1969). „Glucokinase of Dictyostelium discoideum”. Biochemistry 8: 5011-5015. PMID 4312464.
- ↑ Bueding, E. and MacKinnon, J.A. (1955). „Hexokinases of Schistosoma mansoni”. J. Biol. Chem. 215: 495-506. PMID 13242546.
- ↑ Porter, E.V., Chassy, B.M. and Holmlund, C.E. (1982). „Purification and kinetic characterization of a specific glucokinase from Streptococcus mutans OMZ70 cells”. Biochim. Biophys. Acta 709: 178-186. PMID 7150605.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.