Glikogen(skrob) sintaza
Glikogen(skrob) sintaza (EC 2.4.1.11, UDP-glukoza glikogen glukoziltransferaza, glikogen (skrob) sintetaza, UDP-glukoza-glikogen glukoziltransferaza, UDP-glikogen sintaza, UDPG-glikogen sintetaza, UDPG-glikogen transglukozilaza, uridin difosfoglukoza-glikogen glukoziltransferaza) je enzim sa sistematskim imenom UDP-glukoza:glikogen 4-alfa-D-glukoziltransferaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Glikogen(skrob) sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| Identifikatori | |||||||||
| EC broj | 2.4.1.11 | ||||||||
| CAS broj | 9014-56-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- UDP-glukoza + [(1->4)-alfa-D-glukozil]n UDP + [(1->4)-alfa-D-glukozil]n+1
Glikogen sintaza iz životinjskog tkiva je kompleks katalitičkih podjedinica i protein glikogenina.
Reference uredi
- ↑ Algranati, I.D. and Cabib, E. (1960). „The synthesis of glycogen in yeast”. Biochim. Biophys. Acta 43: 141-142. PMID 13682402.
- ↑ Basu, D.K. and Bachhawat, B.K. (1961). „Purification of uridine diphosphoglucose-glycogen transglucosylase from sheep brain”. Biochim. Biophys. Acta 50: 123-128. PMID 13687710.
- ↑ Leloir, L.F. and Cardini, C.E. (1962). „UDPG-glycogen transglucosylase”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 6 (2nd izd.). New York: Academic Press. str. 317-326.
- ↑ Leloir, L.F. and Goldemberg, S.H. (1960). „Synthesis of glycogen from uridine diphosphate glucose in liver”. J. Biol. Chem. 235: 919-923. PMID 14415527.
- ↑ Pitcher, J., Smythe, C. and Cohen, P. (1988). „Glycogenin is the priming glucosyltransferase required for the initiation of glycogen biogenesis in rabbit skeletal muscle”. Eur. J. Biochem. 176: 391-395. PMID 2970965.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
- Leloir, L.F. and Cardini, C.E. (1962). „UDPG-glycogen transglucosylase”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 6 (2nd izd.). New York: Academic Press. str. 317-326.