Benzimidazol – razlika između verzija

Uklonjeni sadržaj Dodani sadržaj
Dcirovicbot (razgovor | doprinos)
r2
 
Dcirovicbot (razgovor | doprinos)
m .
Red 101:
| MeltingPt = 170.5
| Melting_notes =
| BoilingPt = >360 °-{C}-
| Boiling_notes =
| LogP =
Red 175:
}}
}}
'''Benzimidazol''' je [[organsko jedinjenje]], koje sadrži 7 [[atom]]a [[ugljenik]]a i ima [[Молекулска маса|molekulsku masu]] od 117,128 [[Јединица атомске масе|-{Da}-]].<ref>{{cite journal |title = DrugBank 3.0: a comprehensive resource for omics research on drugs |author = Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS |journal = Nucleic Acids Res. |year = 2011 |volume = 39 |issue = Database issue |pages = D1035-41 | pmid =21059682 |doi = 10.1093/nar/gkq1126 |pmc = 3013709}}</ref><ref>{{cite journal |title = DrugBank: a knowledgebase for drugs, drug actions and drug targets |author = Nucleic Acids Res |year = 2008 |volume = 36 |issue = Database issue |pages = D901-6 |pmid = 18048412 |first2 = C |first3 = AC |first4 = D |first5 = S |first6 = D |first7 = B |first8 = M |doi = 10.1093/nar/gkm958 |pmc = 2238889 |journal = Nucleic acids research}}</ref>
== Osobine ==
 
Red 188:
| [[Геометрија молекула|Broj rotacionih veza]] || 0
|-
| [[Particioni koeficijent]]<ref>{{cite journal |author = Ghose, A.K., Viswanadhan V.N., and Wendoloski, J.J. |title = Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods |journal = J. Phys. Chem. A |year = 1998 |volume = 102 |pages = 3762-3772 |url = http://www.citeulike.org/user/gregoryross/article/2886898 |doi = 10.1021/jp980230o |pmid = }}</ref> (-{''ALogP'')}- || 1,3
|-
| [[Rastvorljivost]]<ref>{{cite journal |title = Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices |author = Tetko IV, Tanchuk VY, Kasheva TN, Villa AE. |journal = Chem Inf. Comput. Sci. |year = 2001 |volume = 41 |pages = 1488-1493 |url = http://pubs.acs.org/doi/abs/10.1021/ci000392t |pmid = 11749573 |doi = 10.1021/ci000392t }}</ref> (-{''logS'', log(''mol/L''}-)) || -1,4
|-
| [[Polarna površina molekula|Polarna površina]]<ref>{{cite journal |title = Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties |author = Ertl P., Rohde B., Selzer P. |journal = J. Med. Chem. |year = 2000 |volume = 43 |pages = 3714-3717 |url = http://pubs.acs.org/doi/abs/10.1021/jm000942e | pmid = 11020286 |doi = 10.1021/jm000942e }}</ref> (-{''PSA''}-, [[Ангстрем (јединица)|Å<sup>2</sup>]]) || 28,7
|}
 
Red 207:
{{Portal-lat|Hemija}}
{{Commonscat-lat|Benzimidazole}}
* [http://www.drugbank.ca/drugs/DB02962 -{Benzimidazole}-]
 
[[Категорија:Антелминтици]]