Razlike između izmjena na stranici "Ribavirin"

Obrisano 20 bajtova ,  prije 6 godina
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<!-- Clinical data -->
| tradename = Copegus, Rebetol, Rebetron, Rebretron}-
| Drugs.com = {{drugs.com-lat|monograph|Ribavirin}}
| MedlinePlus =
| sec_combustion =
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'''Ribavirin''' je [[organsko jedinjenje]], koje sadrži 8 [[atom]]a [[ugljenik]]a i ima [[Молекулска маса|molekulsku masu]] od 244,205 [[Јединица атомске масе|Da}-]].<ref>Sidwell RW, Bailey KW, Wong MH, Barnard DL, Smee DF: In vitro and in vivo influenza virus-inhibitory effects of viramidine. Antiviral Res. 2005 Oct;68(1):10-7. [[PubMed|PMID]] [http://www.ncbi.nlm.nih.gov/pubmed/16087250 16087250]}-</ref><ref>Sidwell RW, Huffman JH, Khare GP, Allen LB, Witkowski JT, Robins RK: Broad-spectrum antiviral activity of Virazole: 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide. Science. 1972 Aug 25;177(50): 705-6. [[PubMed|PMID]] [http://www.ncbi.nlm.nih.gov/pubmed/4340949 4340949]}-</ref><ref>Alvarez D, Dieterich DT, Brau N, Moorehead L, Ball L, Sulkowski MS: Zidovudine use but not weight-based ribavirin dosing impacts anaemia during HCV treatment in HIV-infected persons. J Viral Hepat. 2006 Oct;13(10):683-9. [[PubMed|PMID]] [http://www.ncbi.nlm.nih.gov/pubmed/16970600 16970600]}-</ref><ref>Bani-Sadr F, Carrat F, Pol S, Hor R, Rosenthal E, Goujard C, Morand P, Lunel-Fabiani F, Salmon-Ceron D, Piroth L, Pialoux G, Bentata M, Cacoub P, Perronne C: Risk factors for symptomatic mitochondrial toxicity in HIV/hepatitis C virus-coinfected patients during interferon plus ribavirin-based therapy. J Acquir Immune Defic Syndr. 2005 Sep 1;40(1):47-52. [[PubMed|PMID]] [http://www.ncbi.nlm.nih.gov/pubmed/16123681 16123681]}-</ref><ref>{{Cite pmid|21059682|noedit}}</ref><ref>{{cite pmid|18048412|noedit}}</ref>
== Osobine ==
 
| [[Геометрија молекула|Broj rotacionih veza]] || 3
|-
| [[Particioni koeficijent]]<ref>{{cite doi/10.1021/jp980230o|noedit}}</ref> (''ALogP'')}- || -2,7
|-
| [[Rastvorljivost]]<ref>{{cite pmid|11749573|noedit}}</ref> (''logS'', log(''mol/L''}-)) || -0,3
|-
| [[Polarna površina molekula|Polarna površina]]<ref>{{cite pmid|11020286|noedit}}</ref> (''PSA''}-, [[Ангстрем (јединица)|Å<sup>2</sup>]]) || 143,7
|}
 
{{Portal-lat|Medicina|Hemija}}
{{Commonscat-lat|Ribavirin}}
* [http://www.drugbank.ca/drugs/DB00811 Ribavirin}-]
{{Medicinsko upozorenje-lat}}
 
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