Poliribonukleotid nukleotidiltransferaza
(Preusmjereno sa stranice Polinukleotidna fosforilaza)
Poliribonukleotid nukleotidiltransferaza (EC 2.7.7.8, polinukleotidna fosforilaza, PNPaza, nukleozid difosfat:polinukleotidil transferaza, poliribonukleotidna nukleotidiltransferaza, polinukleotidna fosforilaza, poliribonukleotidna fosforilaza) je enzim sa sistematskim imenom poliribonukleotid:fosfat nucleotidiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Poliribonukleotid nukleotidiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Poliribonukleotid nukleotidiltransferaza trimer, Streptomyces antibioticus | |||||||||
| Identifikatori | |||||||||
| EC broj | 2.7.7.8 | ||||||||
| CAS broj | 2598674 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- RNKn+1 + fosfat RNKn + nukleozid difosfat
ADP, IDP, GDP, UDP i CDP mogu da deluju kao donori.
Reference uredi
- ↑ Hakim, A.A. (1959). „Synthetic activity of polynucleotide phosphorylase from sperm”. Nature 183: 334-334. PMID 13632712.
- ↑ Littauer, U.Z. and Kornberg, A. (1957). „Reversible synthesis of polyribonucleotides with an enzyme from Escherichia coli”. J. Biol. Chem. 226: 1077-1092. PMID 13438894.
- ↑ Ochoa, S. and Mii, S. (1961). „Enzymatic synthesis of polynucleotides. IV. Purification and properties of polynucleotide phosphorylase from Azotobacter vinelandii”. J. Biol. Chem. 236: 3303-3311. PMID 14481058.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.