Piridoksamin-fosfat transaminaza
Piridoksamin-fosfat transaminaza (EC 2.6.1.54, piridoksamin fosfatna aminotransferaza, piridoksamin 5'-fosfat-alfa-ketoglutaratna transaminaza, piridoksaminska 5'-fosfat transaminaza) je enzim sa sistematskim imenom piridoksamin-5'-fosfat:2-oksoglutarat aminotransferaza (formira D-glutamat).[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Piridoksamin-fosfat transaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.6.1.54 | ||||||||
| CAS broj | 9074-84-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- piridoksamin 5'-fosfat + 2-oksoglutarat piridoksal 5'-fosfat + D-glutamat
Ovaj enzim takođe u manjoj meri deluje na piridoksamin.
Reference uredi
- ↑ Tani, Y., Ukita, M. and Ogata, K. (1972). „Studies on vitamin B6 metabolism in microorganisms. Part X. Further purification and characterization of pyridoxamine 5′-phosphate-α-ketoglutarate transaminase from Clostridium kainantoi”. Agric. Biol. Chem. 36: 181-188.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.