Pentagastrin je sintetički pentapeptid koji deluje poput gastrina pri parenteralnoj primeni. On stimuliše sekreciju želudačna kiseline i pepsina. Korišten je kao dijagnostičko sredstvo.[4][5][6]

Pentagastrin
(IUPAC) ime
(3S)-3- {[(1S)-1-karbamoil-2-feniletil]karbamoil 3-[(2S)-2-[(2S)-3-(1H-indol-3-il)-2-(3[(2-metilpropoksi)karbonil]amino}propanamido)propanamido]- 4-(metilsulfanil)butanamido]propanoinska kiselina
Klinički podaci
AHFS/Drugs.com Monografija
Identifikatori
CAS broj 5534-95-2
ATC kod V04CG04
PubChem[1][2] 444007
DrugBank DB00183
ChemSpider[3] 392037
Hemijski podaci
Formula C37H49N7O9S 
Mol. masa 767.891
SMILES eMolekuli & PubHem
Fizički podaci
Tačka topljenja 229 °C (444 °F)
Farmakokinetički podaci
Poluvreme eliminacije 10 minuta ili manje
Farmakoinformacioni podaci
Trudnoća ?
Pravni status

ReferenceUredi

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. http://www.sciencedirect.com/science/article/pii/S1359644610007737.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. http://www.jcheminf.com/content/2/1/3.  edit
  4. Weintraub HS, Rudolph A: Combination Therapy for Managing Difficult-to-Treat Patients With Stage 2 Hypertension: Focus on Valsartan-Based Combinations. Am J Ther. 2010 Jun 9. PMID 20535014
  5. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035-41. PMID 21059682. 
  6. Nucleic Acids Res (2008). DrugBank: a knowledgebase for drugs, drug actions and drug targets. 36. pp. D901-6. PMID 18048412. 

Spoljašnje vezeUredi

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