Nitrazin

Nitrazin
	(3E)-3-[(2,4-Dinitrophenyl)hydrazono]-4-oxonaphthalene-2,7-disulfonic acid
Drugi nazivi	Nitrazinsko žuto; fenaftazin
Identifikacija
CAS registarski broj	1716-22-9
PubChem	6911856
ChemSpider	5288340
Jmol-3D slike	Slika 1
SMILES
	[O-][N+](=O)c1ccc(c([N+]([O-])=O)c1)N/N=C3/C(=C\c2c(ccc(c2)S(=O)(=O)O)C3=O)S(=O)(=O)O
InChI
	InChI=1S/C16H10N4O11S2/c21-16-11-3-2-10(32(26,27)28)5-8(11)6-14(33(29,30)31)15(16)18-17-12-4-1-9(19(22)23)7-13(12)20(24)25/h1-7,17H,(H,26,27,28)(H,29,30,31)/b18-15- ; Kod: IHRSXGONVFFQQF-SDXDJHTJSA-N InChI=1/C16H10N4O11S2/c21-16-11-3-2-10(32(26,27)28)5-8(11)6-14(33(29,30)31)15(16)18-17-12-4-1-9(19(22)23)7-13(12)20(24)25/h1-7,17H,(H,26,27,28)(H,29,30,31)/b18-15-; Kod: IHRSXGONVFFQQF-SDXDJHTJBN
Svojstva
Molekulska formula	C16H10N4O11S2
Molarna masa	498.40 g/mol
	(šta je ovo?) (verifikuj) ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

Nitrazin (fenaftazin) je pH indikatorska boja.

Nitrazinski test uredi

U obliku dinatrijumske soli, on se koristi u trakama za pH testiranje u medicinskoj praksi. Test se koristi za određivanje vaginalnog pH tokom kasnog perioda trudnoće radi određivanja otvaranja amnionske kese.^[4] Dok je vaginalni pH normalno kiseo, pH iznad 7.0 može da služi kao indikacija cepanja amnionske kese.^[5] Međutim, povišeni pH isto tako može da bude posledica bakterijske vaginoze.^[6]

On se takođe koristi u građevinarstvu za određivanje raspodele karbonacije u betonskim strukturama i stoga za utvrđivanje stanja pasivacionog filma armature. On je senzitivniji od lakmus papira. Nitrazin daje pH indikaciju u opsegu od 4.5 do 7.5.

Reference uredi

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Erdemoglu E, Mungan T (July 2004). „Significance of detecting insulin-like growth factor binding protein-1 in cervicovaginal secretions: comparison with nitrazine test and amniotic fluid volume assessment”. Acta Obstet Gynecol Scand 83 (7): 622–6. DOI:10.1111/j.0001-6349.2004.00343.x. PMID 15225185.
↑ „Nitrazine paper”.
↑ Sobel JD, Nyirjesy P, Kessary H, Ferris DG (September 2009). „Use of the VS-sense swab in diagnosing vulvovaginitis”. J Womens Health (Larchmt) 18 (9): 1467–70. DOI:10.1089/jwh.2008.1305. PMID 19743911.

Spoljašnje veze uredi

Portal Hemija

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[pmid15225185-4] Erdemoglu E, Mungan T (July 2004). „Significance of detecting insulin-like growth factor binding protein-1 in cervicovaginal secretions: comparison with nitrazine test and amniotic fluid volume assessment”. Acta Obstet Gynecol Scand 83 (7): 622–6. DOI:10.1111/j.0001-6349.2004.00343.x. PMID 15225185.

[5] „Nitrazine paper”.

[pmid19743911-6] Sobel JD, Nyirjesy P, Kessary H, Ferris DG (September 2009). „Use of the VS-sense swab in diagnosing vulvovaginitis”. J Womens Health (Larchmt) 18 (9): 1467–70. DOI:10.1089/jwh.2008.1305. PMID 19743911.

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