Neuromedinski U receptor 2

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Neuromedinski U receptor 2 je protein koji je kod ljudi kodiran NMUR2 genom.

Neuromedinski U receptor 2
Identifikatori
Simboli	NMUR2; FM4; NMU2R
Vanjski ID	OMIM: 605108 MGI: 2441765 HomoloGene: 49618 IUPHAR: NMU2 GeneCards: NMUR2 Gene
Ontologija gena Molekularna funkcija • aktivnost rodopsinu-sličnog receptora • aktivnost neuromedinskog U receptora • receptorska aktivnost • aktivnost intracelularnim kalcijumom aktiviranog hloridnog kanala • GTP vezivanje Celularna komponenta • integralno sa ćelijskom membranom • membrana Biološki proces • transport jona kalcijuma • regulacija kontrakcija glatkih mišića • prenos signala • G-protein signalizacija, spregnuta sa IP3 sekundarnim glasnikom (aktivacija fosfolipaze C) • elevacija koncentracije citosolnih jona kalcijuma • neuropeptidni signalni put • razvoj centralnog nervnog sistema • način ishrane • transmisija nervnog impulsa • aktivacija kalcijum-zavisne fosfolipaze A2 • sekretorni put • inozitol fosfat-posredovana signalizacija • sekrecija arahidonske kiseline
Ortolozi
Vrsta	Čovek	Miš
Entrez	56923	216749
Ensembl	ENSG00000132911	ENSMUSG00000037393
UniProt	Q9GZQ4	Q8BZ39
RefSeq (mRNA)	NM_020167	NM_153079
RefSeq (protein)	NP_064552	NP_694719
Lokacija (UCSC)	Chr 5: 151.75 - 151.77 Mb	Chr 11: 55.87 - 55.88 Mb
PubMed pretraga	[1]	[2]

Vidi još

• Neuromedinski U receptor

Dodatna literatura

• Hosoya M, Moriya T, Kawamata Y, et al. (2000). „Identification and functional characterization of a novel subtype of neuromedin U receptor.”. J. Biol. Chem. 275 (38): 29528–32. DOI:10.1074/jbc.M004261200. PMID 10887190. 
• Raddatz R, Wilson AE, Artymyshyn R, et al. (2000). „Identification and characterization of two neuromedin U receptors differentially expressed in peripheral tissues and the central nervous system.”. J. Biol. Chem. 275 (42): 32452–9. DOI:10.1074/jbc.M004613200. PMID 10899166. 
• Shan L, Qiao X, Crona JH, et al. (2001). „Identification of a novel neuromedin U receptor subtype expressed in the central nervous system.”. J. Biol. Chem. 275 (50): 39482–6. DOI:10.1074/jbc.C000522200. PMID 11010960. 
• Fernández Alvarez C, Debeljuk L, Díaz Rodríguez E, Díaz López B (2003). „Developmental pattern of tachykinins during aging in several organs: effect of exogenous melatonin.”. Peptides 23 (9): 1617–23. DOI:10.1016/S0196-9781(02)00099-2. PMID 12217422. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334. 
• Bhattacharyya S, Luan J, Farooqi IS, et al. (2004). „Studies of the neuromedin U-2 receptor gene in human obesity: evidence for the existence of two ancestral forms of the receptor.”. J. Endocrinol. 183 (1): 115–20. DOI:10.1677/joe.1.05830. PMID 15525579. 
• Mori K, Miyazato M, Ida T, et al. (2005). „Identification of neuromedin S and its possible role in the mammalian circadian oscillator system.”. EMBO J. 24 (2): 325–35. DOI:10.1038/sj.emboj.7600526. PMC 545815. PMID 15635449. 
• Fang L, Zhang M, Li C, et al. (2006). „Chemical genetic analysis reveals the effects of NMU2R on the expression of peptide hormones.”. Neurosci. Lett. 404 (1–2): 148–53. DOI:10.1016/j.neulet.2006.05.034. PMID 16781063. 

Spoljašnje veze

• „Neuromedin U Receptors: NMU2”. IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Arhivirano iz originala na datum 2016-03-03.