N-izopropilamelidna izopropilaminohidrolaza
N-izopropilamelidna izopropilaminohidrolaza (EC 3.5.99.4, AtzC) je enzim sa sistematskim imenom N-izopropilamelid izopropilaminohidrolaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| N-izopropilamelidna izopropilaminohidrolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.99.4 | ||||||||
| CAS broj | 203810-02-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- N-izopropilamelid + H2O cijanurinska kiselina + izopropilamin
Učestvuje u degradaciji herbicida atrazina, 2-hloro-4-(etilamino)-6-(izopropilamino)-1,3,5-triazina, u bakterijama.
Reference uredi
- ↑ Sadowsky, M.J., Tong, Z., de Souza, M. and Wackett, L.P. (1998). „AtzC is a new member of the amidohydrolase protein superfamily and is homologous to other atrazine-metabolizing enzymes”. J. Bacteriol. 180: 152-158. PMID 9422605.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.