Metitepin
(Preusmjereno sa stranice Metiotepin)
Metitepin (INN), isto tako poznat kao metiotepin, je lek koji deluje kao antagonist raznih serotoninskih i dopaminskih receptora.[4][5] On se koristi kao antipsihotik.
| |||
| (IUPAC) ime | |||
|---|---|---|---|
| 1-methyl-4-(8-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-6-yl)piperazine | |||
| Klinički podaci | |||
| Identifikatori | |||
| CAS broj | 20229-30-5 | ||
| ATC kod | ? | ||
| PubChem[1][2] | 4106 | ||
| ChemSpider[3] | 3963 | ||
| UNII | 55D94103HL 
| ||
| Hemijski podaci | |||
| Formula | C20H24N2S2 | ||
| Mol. masa | 356.55 g/mol | ||
| SMILES | eMolekuli & PubHem | ||
| |||
| Farmakoinformacioni podaci | |||
| Trudnoća | ? | ||
| Pravni status | |||
Literatura uredi
- ↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.
- ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
- ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.
- ↑ Monachon MA, Burkard WP, Jalfre M, Haefely W (1972). „Blockade of central 5-hydroxytryptamine receptors by methiothepin”. Naunyn Schmiedebergs Arch. Pharmacol. 274 (2): 192–7. DOI:10.1007/BF00501854. PMID 4340797.
- ↑ Dall'Olio R, Vaccheri A, Montanaro N (1985). „Reduced head-twitch response to quipazine of rats previously treated with methiothepin: possible involvement of dopaminergic system”. Pharmacol. Biochem. Behav. 23 (1): 43–8. DOI:10.1016/0091-3057(85)90128-5. PMID 2994121.
