Magnezijum protoporfirin IX metiltransferaza

Magnezijum protoporfirin IX metiltransferaza
	Magnezijum protoporfirin IX O-metiltransferaza homodimer, Synechocystis
Identifikatori
EC broj	2.1.1.11
CAS broj	9029-82-7
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC	articles
PubMed	articles
NCBI Protein	search

Magnezijum protoporfirin IX metiltransferaza (EC 2.1.1.11, Magnesium protoporphyrin IX methyltransferase) je enzim sa sistematskim imenom S-adenozil-L-metionin:magnezijum-protoporfirin-IX O-metiltransferaza.^[1]^[2]^[3]^[4]^[5] Ovaj enzim katalizuje sledeću hemijsku reakciju

S-adenozil-L-metionin + magnezijum protoporfirin IX

\rightleftharpoons

S-adenozil-L-homocistein + magnezijum protoporfirin IX 13-metil estar

Reference uredi

↑ Gibson, K.D., Neuberger, A. and Tait, G.H. (1963). „Studies on the biosynthesis of porphyrin and bacteriochlorophyll by Rhodopseudomonas spheroides. 4. S-Adenosylmethioninemagnesium protoporphyrin methyltransferase”. Biochem. J. 88: 325-334. PMID 14063871.
↑ Shepherd, M., Reid, J.D. and Hunter, C.N. (2003). „Purification and kinetic characterisation of the magnesium protoporphyrin IX methyltransferase from Synechocystis PCC6803”. Biochem. J. 371: 351-360. PMID 12489983.
↑ Bollivar, D.W., Jiang, Z.Y., Bauer, C.E. and Beale, S.I. (1994). „Heterologous expression of the bchM gene product from Rhodobacter capsulatus and demonstration that it encodes S-adenosyl-L-methionine:Mg-protoporphyrin IX methyltransferase”. J. Bacteriol. 176: 5290-5296. PMID 8071204.
↑ Gibson, L.C. and Hunter, C.N. (1994). „The bacteriochlorophyll biosynthesis gene, bchM, of Rhodobacter sphaeroides encodes S-adenosyl-L-methionine: Mg protoporphyrin IX methyltransferase”. FEBS Lett. 352: 127-130. PMID 7925960.
↑ Ebbon, J.G. and Tait, G.H. (1969). „Studies on S-adenosylmethionine-magnesium protoporphyrin methyltransferase in Euglena gracilis strain Z”. Biochem. J. 111: 573-582. PMID 5774480.

Literatura uredi

Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.

Spoljašnje veze uredi

MeSH Magnesium+protoporphyrin+IX+methyltransferase

[1] Gibson, K.D., Neuberger, A. and Tait, G.H. (1963). „Studies on the biosynthesis of porphyrin and bacteriochlorophyll by Rhodopseudomonas spheroides. 4. S-Adenosylmethioninemagnesium protoporphyrin methyltransferase”. Biochem. J. 88: 325-334. PMID 14063871.

[2] Shepherd, M., Reid, J.D. and Hunter, C.N. (2003). „Purification and kinetic characterisation of the magnesium protoporphyrin IX methyltransferase from Synechocystis PCC6803”. Biochem. J. 371: 351-360. PMID 12489983.

[3] Bollivar, D.W., Jiang, Z.Y., Bauer, C.E. and Beale, S.I. (1994). „Heterologous expression of the bchM gene product from Rhodobacter capsulatus and demonstration that it encodes S-adenosyl-L-methionine:Mg-protoporphyrin IX methyltransferase”. J. Bacteriol. 176: 5290-5296. PMID 8071204.

[4] Gibson, L.C. and Hunter, C.N. (1994). „The bacteriochlorophyll biosynthesis gene, bchM, of Rhodobacter sphaeroides encodes S-adenosyl-L-methionine: Mg protoporphyrin IX methyltransferase”. FEBS Lett. 352: 127-130. PMID 7925960.

[5] Ebbon, J.G. and Tait, G.H. (1969). „Studies on S-adenosylmethionine-magnesium protoporphyrin methyltransferase in Euglena gracilis strain Z”. Biochem. J. 111: 573-582. PMID 5774480.

[1]

[2]

[3]

[4]

[5]