Lipoamid

Lipoamid
	5-(1,2-ditiolan-3-il)pentanamid
Identifikacija
CAS registarski broj	940-69-2
PubChem	6992093
ChemSpider	5360246
MeSH	lipoamide
Jmol-3D slike	Slika 1
SMILES
	O=C(N)CCCC[C@H]1SSCC1
InChI
	InChI=1S/C8H15NOS2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H2,9,10)/t7-/m1/s1 ; Kod: FCCDDURTIIUXBY-SSDOTTSWSA-N InChI=1/C8H15NOS2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H2,9,10)/t7-/m1/s1; Kod: FCCDDURTIIUXBY-SSDOTTSWBG
Svojstva
Molekulska formula	C8H15NOS2
Molarna masa	205.34 g mol−1
	(šta je ovo?) (verifikuj) ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

Lipoamid je trivijalno ime za 6,8-ditiooktanski amid. On je funkciona forma 6,8-ditiooktanske kiseline u kojoj je karboksilna grupa vezana za protein (ili neki drugi amin) putem amidne veze (sadrži -NH₂). U nekim slučajevima se termin lipoamid koristi za proteine vezane za lipoinsku kiselinu, mada je to tehnički nekorektno. Lipoil-protein ili lipoil-domen su podesniji termini za proteine vezane za lipoinsku kiselinu.

Slobodni lipoamid se ne javlja u prirodi.

Reference Uredi

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

Literatura Uredi

R L Krauth-Siegel and R Schöneck (September 1995). „Flavoprotein structure and mechanism. 5. Trypanothione reductase and lipoamide dehydrogenase as targets for a structure-based drug design”. FASEB Journal 9: 1138-1146.

Vidi još Uredi

Lipoinska kiselina

Spoljašnje veze Uredi

Portal Hemija

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

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