Lakaza
Lakaza (EC 1.10.3.2, urishiol oksidaza, urušiol oksidaza, p-difenolna oksidaza) je enzim sa sistematskim imenom benzendiol:kiseonik oksidoreduktaza.[1][2][3][4][5][6][7][8] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Lakaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.10.3.2 | ||||||||
| CAS broj | 80498-15-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 4 benzendiol + O2 4 benzosemihinon + 2H2O
Ova grupa multi-bakarnih proteina ima nisku specifičnost za o- i p-hinole. Oni takođe često deluju na aminofenole i fenilendiamine.
Reference uredi
- ↑ Dawson, C.R. and Tarpley, W.B. (1951). „The copper oxidases”. u: Sumner, J.B. and Myrbäck, K.. The Enzymes. 2 (1st izd.). New York: Academic Press. str. 454-498.
- ↑ Keilin, D. and Mann, T. (1939). „Laccase, a blue copper-protein oxidase from the latex of Rhus succedanea”. Nature (Lond.) 143: 23-24.
- ↑ Malmström, B.G., Andréasson, L.-E. and Reinhammar, B. (1975). „Copper-containing oxidases and superoxide dismutase”. u: Boyer, P.D.. The Enzymes. 12 (3rd izd.). New York: Academic Press. str. 507-579.
- ↑ Mayer, A.M. and Harel, E. (1979). „Polyphenol oxidases in plants”. Phytochemistry 18: 193-215.
- ↑ Nakamura, T. (1958). „Purification and physico-chemical properties of laccase”. Biochim. Biophys. Acta 30: 44-52. PMID 13584395.
- ↑ Nakamura, T. (1958). „Stoichiometric studies on the action of laccase”. Biochim. Biophys. Acta 30: 538-542. PMID 13618260.
- ↑ Peisach, J. and Levine, W.G. (1965). „A comparison of the enzymic activities of pig ceruloplasmin and Rhus vernicifera laccase”. J. Biol. Chem. 240: 2284-2289. PMID 14304827.
- ↑ Reinhammar, B. and Malmström, B.G. (1981). „"Blue" copper-containing oxidases”. u: Spiro, T.G.. Copper Proteins. New York: Copper Proteins. str. 109-149.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.