Kafeat O-metiltransferaza
Kafeat O-metiltransferaza (EC 2.1.1.68, kafeatna metiltransferaza, kafeatna 3-O-metiltransferaza, S-adenozil-L-metionin:kafeinska kiselina-O-metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:3,4-dihidroksi-trans-cinamat 3-O-metiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Kafeat O-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.68 | ||||||||
| CAS broj | 50936-45-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- S-adenozil-L-metionin + 3,4-dihidroksi-trans-cinamat S-adenozil-L-homocistein + 3-metoksi-4-hidroksi-trans-cinamat
3,4-Dihidroksibenzaldehid i katehol mogu da deluju kao akceptori, mada je reakcija sporija.
Reference uredi
- ↑ Ebel, J., Schaller-Hekeler, B., Knobloch, K.-H., Wellman, E., Grisebach, H. and Hahlbrock, K. (1974). „Coordinated changes in enzyme activities of phenylpropanoid metabolism during the growth of soybean cell suspension cultures”. Biochim. Biophys. Acta 362: 417-424. PMID 4472044.
- ↑ Poulton, J.E. and Butt, V.S. (1975). „Purification and properties of S-adenosyl-L-methionine: caffeic acid O-methyltransferase from leaves of spinach beet (Beta vulgaris L)”. Biochim. Biophys. Acta 403: 301-314. PMID 241400.
- ↑ Shimada, M., Kuroda, H. and Higuchi, T. (1973). „Evidence for the formation of methoxyl groups of ferulic and sinapic acid in Bambusa by the same O-methyltransferase”. Phytochemistry 12: 2873-2875.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.