Izomaltulozna sintaza
Izomaltulozna sintaza (EC 5.4.99.11, isomaltulozna sintetaza, saharozna alfa-glukoziltransferaza, trehalulozna sintaza) je enzim sa sistematskim imenom saharoza glukozilmutaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Izomaltulozna sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 5.4.99.11 | ||||||||
| CAS broj | 159940-49-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- saharoza 6-O-alfa-D-glukopiranozil-D-fruktofuranoza
Ovaj enzim simultano formira izomaltulozu (6-O-alfa-D-glukopiranozil-D-fruktozu) i manje količine trehaluloze (1-O-alfa-D-glukopiranozil-beta-D-fruktoze) iz saharoze.
Reference
uredi- ↑ Cheetham, P.S.J. (1984). „The extraction and mechanism of a novel isomaltulose-synthesizing enzyme from Erwinia rhapontici”. Biochem. J. 220: 213-220. PMID 6743261.
- ↑ Cheetham, P.S.J., Imber, C.E. and Isherwood, J. (1982). „The formation of isomaltulose by immobilized Erwinia rhapontici”. Nature 299: 628-631.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.