Inozitol 4-metiltransferaza
Inozitol 4-metiltransferaza (EC 2.1.1.129, mio-inozitol 4-O-metiltransferaza, S-adenozil-L-metionin:mio-inozitol 4-O-metiltransferaza, mio-inozitol 6-O-metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:1D-mio-inozitol 4-metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Inozitol 4-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.129 | ||||||||
| CAS broj | 169277-48-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- S-adenozil-L-metionin + mio-inozitol S-adenozil-L-homocistein + 1D-4-O-metil-mio-inozitol
Enzim iz zrna pirinča Vigna umbellata (Fabaceae) je visoko specifičan za S-adenozil-L-metionin.
Reference uredi
- ↑ Vernon, D.M., Bohnert, H.J. (1992). „A novel methyl transferase induced by osmotic stress in the facultative halophyte Mesembryanthemum crystallinum”. EMBO J. 11: 2077-2085. PMID 1600940.
- ↑ Wanek, W. and Richter, A. (1995). „Purification and characterization of myo-inositol 6-O-methyltransferase from Vigna umbellata Ohwi et Ohashi”. Planta 197: 427-434.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.