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GRIP1Gl (gutamatni receptor - interagujući protein 1) je protein koji je kod ljudi kodiran GRIP1 genom.[1][2]

GRIP1

PDB prikaz baziran na 1m5z.
Dostupne strukture
2JIL
Identifikatori
SimboliGRIP1; GRIP
Vanjski IDOMIM604597 MGI1921303 HomoloGene12938 GeneCards: GRIP1 Gene
Pregled RNK izražavanja
podaci
Ortolozi
VrstaČovekMiš
Entrez2342674053
EnsemblENSG00000155974ENSMUSG00000034813
UniProtQ9Y3R0Q925T6
RefSeq (mRNA)NM_001178074.1NM_028736.1
RefSeq (protein)NP_001171545.1NP_083012.1
Lokacija (UCSC)Chr 12:
66.74 - 67.2 Mb
Chr 10:
118.89 - 119.52 Mb
PubMed pretraga[1][2]

Interakcije uredi

GRIP1 (gen) formira interakcije sa GRIA4,[3] metabotropnim glutamatnim receptorom,[3] GRIK2,[3][4] GRIK3,[3] GRIPAP1,[5] GRIA2[3] i GRIA3.[3]

Reference uredi

  1. Bruckner K, Pablo Labrador J, Scheiffele P, Herb A, Seeburg PH, Klein R (April 1999). „EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains”. Neuron 22 (3): 511–24. DOI:10.1016/S0896-6273(00)80706-0. PMID 10197531. 
  2. „Entrez Gene: GRIP1 glutamate receptor interacting protein 1”. 
  3. 3,0 3,1 3,2 3,3 3,4 3,5 Hirbec, Hélène; Perestenko Olga, Nishimune Atsushi, Meyer Guido, Nakanishi Shigetada, Henley Jeremy M, Dev Kumlesh K (May 2002). „The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs”. J. Biol. Chem. (United States) 277 (18): 15221–4. DOI:10.1074/jbc.C200112200. ISSN 0021-9258. PMID 11891216. 
  4. Hirbec, Hélène; Francis Joanna C, Lauri Sari E, Braithwaite Steven P, Coussen Françoise, Mulle Christophe, Dev Kumlesh K, Coutinho Victoria, Meyer Guido, Isaac John T R, Collingridge Graham L, Henley Jeremy M, Couthino Victoria (February 2003). „Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP”. Neuron (United States) 37 (4): 625–38. DOI:10.1016/S0896-6273(02)01191-1. ISSN 0896-6273. PMID 12597860. 
  5. Ye, B; Liao D, Zhang X, Zhang P, Dong H, Huganir R L (June 2000). „GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex”. Neuron (UNITED STATES) 26 (3): 603–17. DOI:10.1016/S0896-6273(00)81198-8. ISSN 0896-6273. PMID 10896157. 

Literatura uredi