Plazmin
(Preusmjereno sa stranice Fibrinolizin)
Plazmin (EC 3.4.21.7, fibrinolizin, aktaza, serumska triptaza, trombolizin) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Plazmin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| Identifikatori | |||||||||
| EC broj | 3.4.21.7 | ||||||||
| CAS broj | 9001-90-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Selektivno razlaganje: Lys- > Arg-; veća selektivnost od tripsina. Konvertuje fibrin u rastvorne produkte
Ovaj enzim se formira proteolizom iz plazminogena.
Reference uredi
- ↑ Castellino, F.J. and Sodetz, J.M. (1976). „Rabbit plasminogen and plasmin isozymes”. Methods Enzymol. 45: 273-286. PMID 138065.
- ↑ Castellino, F.J. and Powell, J.R. (1981). „Human plasminogen”. Methods Enzymol. 80: 365-378. PMID 6210827.
- ↑ Robbins, K.C., Summaria, L. and Wohl, R.C. (1981). „Human plasmin”. Methods Enzymol. 80: 379-387. PMID 6210828.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.