Ferohelataza (EC 4.99.1.1, fero-protoporfirin helataza, gvožđe helataza, hem sintetaza, hem sintaza, protoheme fero-lijaza) je enzim sa sistematskim imenom protohem fero-lijaza (formira protoporfirin).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

Ferohelataza
Protein FECH PDB 1hrk.png
Identifikatori
EC broj 4.99.1.1
CAS broj 9012-93-5
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures
protohem + 2 H+ protoporfirin + Fe2+

ReferenceUredi

  1. Bloomer, J.R., Hill, H.D., Morton, K.O., Anderson-Burnham, L.A. and Straka, J.G. (1987). "The enzyme defect in bovine protoporphyria. Studies with purified ferrochelatase". J. Biol. Chem. 262: 667–671. PMID 3805002. 
  2. Porra, R.J. and Jones, O.T. (1963). "Studies on ferrochelatase. 1. Assay and properties of ferrochelatase from a pig-liver mitochondrial extract". Biochem. J. 87: 181–185. PMID 13972328. 
  3. Porra, R.J. and Jones, O.T. (1963). "Studies on ferrochelatase. 2. An investigation of the role of ferrochelatase in the biosynthesis of various haem prosthetic groups". Biochem. J. 87: 186–192. PMID 13972329. 

LiteraturaUredi

Spoljašnje vezeUredi