Ekvilibrativni nukleozidni transporter
Ekvilibrativni nukleozidni transporter (ENT familija, SLC29) je grupa membranskih transportnih proteina koji transportuju nukleozidne supstrate poput adenozina u ćelije.[1] Poznata su četiri ENT proteina: ENT1, ENT2, ENT3, i ENT4.[1][2] ENT proteini se blokiraju inhibitorima preuzimanja adenozina kao što su dipiridamol i dilazep, lekovima sa kliničkom primenom kao vazodilatatori.[2][3]
Reference uredi
- ↑ 1,0 1,1 Baldwin SA, Beal PR, Yao SY, King AE, Cass CE, Young JD (February 2004). „The equilibrative nucleoside transporter family, SLC29”. Pflügers Archiv : European Journal of Physiology 447 (5): 735–43. DOI:10.1007/s00424-003-1103-2. PMID 12838422.
- ↑ 2,0 2,1 Molina-Arcas M, Casado FJ, Pastor-Anglada M (October 2009). „Nucleoside transporter proteins”. Current Vascular Pharmacology 7 (4): 426–34. PMID 19485885. Arhivirano iz originala na datum 2013-01-13. Pristupljeno 2021-08-20.
- ↑ Noji T, Karasawa A, Kusaka H (July 2004). „Adenosine uptake inhibitors”. European Journal of Pharmacology 495 (1): 1–16. DOI:10.1016/j.ejphar.2004.05.003. PMID 15219815.
Literatura uredi
- Molina-Arcas M, Casado FJ, Pastor-Anglada M (October 2009). „Nucleoside Transporter Proteins”. Current Vascular Pharmacology 7 (4): 426–34. PMID 19485885. Arhivirano iz originala na datum 2013-01-13. Pristupljeno 2021-08-20.
- Baldwin SA, Beal PR, Yao SY, King AE, Cass CE, Young JD (February 2004). „The equilibrative nucleoside transporter family, SLC29”. Pflügers Archiv : European Journal of Physiology 447 (5): 735–43. DOI:10.1007/s00424-003-1103-2. PMID 12838422.
- Molina-Arcas M, Trigueros-Motos L, Casado FJ, Pastor-Anglada M (June 2008). „Physiological and pharmacological roles of nucleoside transporter proteins”. Nucleosides, Nucleotides & Nucleic Acids 27 (6): 769–78. DOI:10.1080/15257770802145819. PMID 18600539.