Ekonazol

Ekonazol
(IUPAC) ime
	(RS)-12-[(4-hlorofenil)metoksi]-2-(2,4-dihlorofenil)etil1H-imidazol
Klinički podaci
AHFS/Drugs.com	Monografija
MedlinePlus	a684049
Identifikatori
CAS broj	27220-47-9
ATC kod	D01AC03 G01AF05
PubChem	3198
DrugBank	DB01127
ChemSpider	3086
UNII	6Z1Y2V4A7M
KEGG	D03936
ChEBI	CHEBI:4754
ChEMBL	CHEMBL808
Hemijski podaci
Formula	C18H15Cl3N2O
Mol. masa	381,683 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C18H15Cl3N2O/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21/h1-9,12,18H,10-11H2 ; Key: LEZWWPYKPKIXLL-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

Ekonazol nitrat je antifungalni lek iz imidazolne klase.^[6] On se koristi u obliku krema za tretiranje kožnih infekcija, kao što su atletsko stopalo, mikoza, dermatofitoza, i Tinea cruris. Dostupan je pod imenima: Spectazole (SAD), Ecostatin (Kanada), Pevaryl (Zapadna Evropa) i Pevisone (kombinacija ekonazol/triamcinolon).^[7]

Reference uredi

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Thienpont, D; Van Cutsem, J; Van Nueten, JM; Niemegeers, CJ; Marsboom, R (1975). „Bilogical and toxicological properties of econazole, a broad-spectrum antimycotic”. Arzneimittel-Forschung 25 (2): 224–30. PMID 1173036.
↑ Product descriptions Arhivirano 2011-08-31 na Wayback Machine-u at REPHCO Pharmaceuticals Limited, Bangladesh. Retrieved June 2012

Spoljašnje veze uredi

	Portal Medicina
	Portal Hemija

Description and details at Drugs.com

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[4] Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG”. Yeast 17 (1): 48–55. DOI:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H.

[5] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit

[6] Thienpont, D; Van Cutsem, J; Van Nueten, JM; Niemegeers, CJ; Marsboom, R (1975). „Bilogical and toxicological properties of econazole, a broad-spectrum antimycotic”. Arzneimittel-Forschung 25 (2): 224–30. PMID 1173036.

[7] Product descriptions Arhivirano 2011-08-31 na Wayback Machine-u at REPHCO Pharmaceuticals Limited, Bangladesh. Retrieved June 2012

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