Diaminopimelinska kiselina

Diaminopimelinska kiselina
	(2R,6S)-2,6-Diaminoheptanedionska kiselina
Identifikacija
CAS registarski broj	583-93-7
PubChem	1549101
ChemSpider	89700
MeSH	Diaminopimelic+acid
ChEBI	16488
ChEMBL	CHEMBL415306
Jmol-3D slike	Slika 1
SMILES
	O=C(O)[C@@H](N)CCC[C@@H](N)C(=O)O
InChI
	InChI=1S/C7H14N2O4/c8-4(6(10)11)2-1-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)/t4-,5+ ; Kod: GMKMEZVLHJARHF-SYDPRGILSA-N InChI=1/C7H14N2O4/c8-4(6(10)11)2-1-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)/t4-,5+; Kod: GMKMEZVLHJARHF-SYDPRGILBU
Svojstva
Molekulska formula	C7H14N2O4
Molarna masa	190.2 g mol−1
Agregatno stanje	beli prah
Gustina	1,344 g/mL
Tačka topljenja	295 °C, 568 K, 563 °F
Tačka ključanja	426.7 °C, 700 K, 800 °F
Opasnost
Opasnost u toku rada	Irritant
	(šta je ovo?) (verifikuj) ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

Diaminopimelinska kiselina (DAP) je aminokiselina. Ona je derivat epsilon-karboksi lizina.

DAP je karakteristična za pojedine bakterijske ćelijske zidove.^[5] U njenom prisustvu, te bakterije normalno rastu, dok u okolnositma DAP deficijencije, one rastu ali ne mogu da formiraju novi proteoglikan ćelijskog zida.

Diaminopimelinska kiselina je isto tako tačka vezivanja Braunovog lipoproteina.^[6]

Reference uredi

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Brooks, George H.; Geo F. Brooks (2007). Jawetz, Melnick & Adelberg's medical microbiology. McGraw-Hill Medical. str. 85. ISBN 0-07-147666-0.
↑ Seltmann, Guntram; Holst, Otto (2002). The Bacterial Cell Wall. Berlin: Springer. str. 81–82. ISBN 3-540-42608-6.

Vidi još uredi

Spoljašnje veze uredi

Portal Hemija

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[4] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit

[isbn0-07-147666-0-5] Brooks, George H.; Geo F. Brooks (2007). Jawetz, Melnick & Adelberg's medical microbiology. McGraw-Hill Medical. str. 85. ISBN 0-07-147666-0.

[6] Seltmann, Guntram; Holst, Otto (2002). The Bacterial Cell Wall. Berlin: Springer. str. 81–82. ISBN 3-540-42608-6.

[1]

[2]

[3]

[4]

[5]

[6]