DNK polimeraza delta
DNK polimeraza delta je enzimski kompleks nađen kod eukariota koji učestvuje u replikaciji i popravci DNK. On se sastoji od proliferativnog ćelijskog nukleusnog antigena (PCNA), višekomponentnog replikacionog faktora C, i 4 podjedinice polimeraznog kompleksa: POLD1, POLD2, POLD3 i POLD4.[1]
| DNK-usmerena DNK polimeraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.7.7 | ||||||||
| CAS broj | 9012-90-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Reference uredi
- ↑ Liu G, Warbrick E (October 2006). „The p66 and p12 subunits of DNA polymerase delta are modified by ubiquitin and ubiquitin-like proteins”. Biochem. Biophys. Res. Commun. 349 (1): 360–6. DOI:10.1016/j.bbrc.2006.08.049. PMID 16934752.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.