Ca2+ transportujuća ATPaza
Ca2+ transportujuća ATPaza (EC 3.6.3.8, ATPaza sarkoplazmičnog retikuluma, Ca2+-ATPaza sarko(endo)plazmičnog retikuluma, kalcijumska pumpa, Ca2+-pumpajuća ATPaza, plazmeno membranska Ca-ATPaza) je enzim sa sistematskim imenom ATP fosfohidrolaza (Ca2+ transport).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Ca2+ transportujuća ATPaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifikatori | |||||||||
| EC broj | 3.6.3.8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Ova P-tip ATPaza podleže kovalentnoj fosforilaciji tokom transportnog ciklusa.
Reference uredi
- ↑ Schatzmann, H.J. and Vicenzi, F.F. (1969). „Calcium movements across the membrane of human red cells”. J. Physiol. 201: 369-395. PMID 4238381.
- ↑ Inesi, G., Watanabe, T., Coan, C. and Murphy, A. (1982). „The mechanism of sarcoplasmic reticulum ATPase”. Ann. N.Y. Acad. Sci. 402: 515-532. PMID 6301340.
- ↑ Carafoli, E. (1992). „The Ca2+ pump of the plasma membrane”. J. Biol. Chem. 267: 2115-2118. PMID 1310307.
- ↑ MacLennan, D.H., Rice, W.J. and Green, N.M. (1997). „The mechanism of Ca2+ transport by sarco(endo)plasmic reticulum Ca2+-ATPases”. J. Biol. Chem. 272: 28815-28818. PMID 9360942.
- ↑ Toyoshima, C., Nakasako, M., Nomura, H. and Ogawa, H. (2000). „Crystal structure of the calcium pump of sarcoplasmic reticulum at 2.6 Å resolution”. Nature 405: 647-655. PMID 10864315.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.