beta-Karbolin

β-Karbolin
	9H-β-karbolin
Drugi nazivi	9H-pirido[3,4-b]indol
Identifikacija
CAS registarski broj	244-63-3
PubChem	64961
ChemSpider	58486
MeSH	norharman
ChEBI	109895
ChEMBL	CHEMBL275224
Jmol-3D slike	Slika 1
SMILES
	c2cncc3nc1ccccc1c23
InChI
	InChI=1S/C11H8N2/c1-2-4-10-8(3-1)9-5-6-12-7-11(9)13-10/h1-7,13H ; Kod: AIFRHYZBTHREPW-UHFFFAOYSA-N InChI=1/C11H8N2/c1-2-4-10-8(3-1)9-5-6-12-7-11(9)13-10/h1-7,13H; Kod: AIFRHYZBTHREPW-UHFFFAOYAG
Svojstva
Molekulska formula	C11H8N2
Molarna masa	168,20 g/mol
	(šta je ovo?) (verifikuj) ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

β-Karbolin (9H-pirido[3,4-b]indol, norharman) je heterociklično jedinjenje koje sadrži azot. On je osnova klase jedinjenja poznatih kao β-karbolini.^[5]^[6]

StrukturaUredi

β-Karbolin pripada grupi [[indolni alkaloid| Beilstein = 7 | pages = 1407–11 | pmid = 22043251 | pmc = 3201054}}</ref> Različiti nivoi zasićenja su mogući u trećem prstenu, što je označeno u donjoj strukturnoj formuli obojenim dvostrukim vezama: | Gmelin = | 3DMet =

Primeri β-karbolinaUredi

Neki od važnijih β-karbolina su navedeni u ovoj tabeli.

Kratko ime	Crvena veza	Plava veza	R1	R6	R7	Struktura
β-Karbolin	×	×	H	H	H
Triptolin			H	H	H
Pinolin			H	OCH₃	H
Harman	×		CH₃	H	H
Harmin	×	×	CH₃	H	OCH₃
Harmalin	×		CH₃	H	OCH₃
Tetrahidroharmin			CH₃	HH	OCH₃

ReferenceUredi

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit
↑ Katritzky A.R., Pozharskii A.F. (2000). Handbook of Heterocyclic Chemistry. Academic Press. ISBN 0080429882.
↑ Clayden Jonathan, Nick Greeves, Stuart Warren, Peter Wothers (2001). Organic chemistry. Oxford, Oxfordshire: Oxford University Press. ISBN 0-19-850346-6.

LiteraturaUredi

Spoljašnje vezeUredi

Portal Hemija

MeSH Beta-Carbolines
TiHKAL #44
Farzin D, Mansouri N (July 2006). „Antidepressant-like effect of harmane and other beta-carbolines in the mouse forced swim test”. Eur Neuropsychopharmacol 16 (5): 324–8. DOI:10.1016/j.euroneuro.2005.08.005. PMID 16183262.

[1] Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit

[2] Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.

[3] Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit

[4] Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594. edit

[Katritzky2nd-5] Katritzky A.R., Pozharskii A.F. (2000). Handbook of Heterocyclic Chemistry. Academic Press. ISBN 0080429882.

[Clayden1st-6] Clayden Jonathan, Nick Greeves, Stuart Warren, Peter Wothers (2001). Organic chemistry. Oxford, Oxfordshire: Oxford University Press. ISBN 0-19-850346-6.

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