Alkohol oksidaza
Alkohol oksidaza (EC 1.1.3.13, etanolna oksidaza) je enzim sa sistematskim imenom alkohol:kiseonik oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Alkohol oksidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| Oktamer alkohol oksidaze (Pichia pastoris) | |||||||||
| Identifikatori | |||||||||
| EC broj | 1.1.3.13 | ||||||||
| CAS broj | 9073-63-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- primarni alkohol + O2 aldehid +H2O2
Ovaj enzim je flavoprotein (FAD). On deluje na niže primarne alkohole i na nezasićene alkohole. Neaktivan je na alkoholima razgranatog lanca i na sekundarnim alkoholima.
Reference uredi
- ↑ Janssen, F.W. and Ruelius, H.W. (1968). „Alcohol oxidase, a flavoprotein from several Basidiomycetes species. Crystallization by fractional precipitation with polyethylene glycol”. Biochim. Biophys. Acta 151: 330-342. PMID 5636370.
- ↑ Nishida, A., Ishihara, T. and Hiroi, T. (1987). „Studies on enzymes related to lignan biodegradation”. Baiomasu Henkan Keikaku Kenkyu Hokoku: 38-59.
- ↑ Suye, S. (1997). „Purification and properties of alcohol oxidase from Candida methanosorbosa M-2003”. Curr. Microbiol. 34: 374-377. PMID 9142745.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.