Alfa-manozidaza
Alfa-manozidaza (EC 3.2.1.24, alfa-D-manozidaza, p-nitrofenil-alfa-manozidaza, alfa-D-manopiranozidaza, 1,2-alfa-manozidaza, 1,2-alfa-D-manozidaza, ekso-alfa-manozidaza) je enzim sa sistematskim imenom alfa-D-manozid manohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Alfa-manozidaza | |||||||||
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| Identifikatori | |||||||||
| EC broj | 3.2.1.24 | ||||||||
| CAS broj | 9025-42-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- hidroliza terminalnih, neredukujućih alfa-D-manoznih ostataka u alfa-D-manozidima
Ovaj enzim takođe hidrolizuje alfa-D-liksozide i heptopiranozide.
Reference uredi
- ↑ Li, Y.-T. (1966). „Presence of α-D-mannosidic linkage in glycoproteins. Liberation of D-mannose from various glycoproteins by α-mannosidase isolated from jack bean meal”. J. Biol. Chem. 241: 1010-1012. PMID 5905120.
- ↑ Winchester, B. (1984). „Role of α-D-mannosidases in the biosynthesis and catabolism of glycoproteins”. Biochem. Soc. Trans. 12: 522-524. PMID 6428944.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.