Acil-KoA dehidrogenaza
Acil-KoA dehidrogenaza (EC 1.3.99.3, acilna dehidrogenaza, masna acil koenzim A dehidrogenaza, acil koenzim A dehidrogenaza, masna-acil-KoA dehidrogenaza, acil KoA dehidrogenaza, general acil KoA dehidrogenaza, acil lanca srednje dužine koenzim A dehidrogenaza, acil lanca srednje dužine KoA dehidrogenaza, acil-KoA:(akceptor) 2,3-oksidoreduktaza) je enzim sa sistematskim imenom acil-KoA:akceptor 2,3-oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju:
| Acil-KoA dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.3.99.3 | ||||||||
| CAS broj | 9027-65-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- acil-KoA + akceptor 2,3-dehidroacil-KoA + redukovani akceptor
Ovaj flavoprotein je deo sistema koji redukuje ubihinon i druge akceptore.
Reference uredi
- ↑ Beinert, H. (1963). „Acyl coenzyme A dehydrogenase”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 7 (2nd izd.). New York: Academic Press. str. 447-466.
- ↑ Crane, F.L., Mii, S., Hauge, J.G., Green, D.E. and Beinert, H. (1956). „On the mechanism of dehydrogenation of fatty acyl derivatives of coenzyme A. I. The general fatty acyl coenzyme A dehydrogenase”. J. Biol. Chem. 218: 701-716. PMID 13295224.
- ↑ Hauge, J.G., Crane, F.L. and Beinert, H. (1956). „On the mechanism of dehydrogenation of fatty acyl derivatives of coenzyme A. III. Palmityl CoA dehydrogenase”. J. Biol. Chem. 219: 727-733. PMID 13319294.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.