5-metiltetrahidrosarcinapterin:korinoid/gvožđe-sumpor protein Co-metiltransferaza
5-metiltetrahidrosarcinapterin:korinoid/gvožđe-sumpor protein Co-metiltransferaza (EC 2.1.1.245, cdhD (gen), cdhE (gen)) je enzim sa sistematskim imenom 5-metiltetrahidrosarcinapterin:korinoid/gvožđe-sumporna proteinska metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 5-metiltetrahidrosarcinapterin:korinoid/gvožđe-sumpor protein Co-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.245 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- [metil-Co(III) korinoid Fe-S protein] + tetrahidrosarcinapterin [Co(I) korinoid Fe-S protein] + 5-metiltetrahidrosarcinapterin
Ovaj enzim katalizuje transfer metil grupa sa kobamidnog kofaktora korinoid/Fe-S proteina na N5 grupu tetrahidrosarcinapterina.
Reference uredi
- ↑ Maupin-Furlow, J. and Ferry, J.G. (1996). „Characterization of the cdhD and cdhE genes encoding subunits of the corrinoid/iron-sulfur enzyme of the CO dehydrogenase complex from Methanosarcina thermophila”. J. Bacteriol. 178: 340-346. PMID 8550451.
- ↑ Grahame, D.A. and DeMoll, E. (1996). „Partial reactions catalyzed by protein components of the acetyl-CoA decarbonylase synthase enzyme complex from Methanosarcina barkeri”. J. Biol. Chem. 271: 8352-8358. PMID 8626532.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.