5-Nitroantranilno kiselinska aminohidrolaza
5-Nitroantranilno kiselinska aminohidrolaza (EC 3.5.99.8, naaA (gen), 5NAA deaminaza) je enzim sa sistematskim imenom 5-nitroantranilat amidohidrolaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 5-Nitroantranilno kiselinska aminohidrolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.99.8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 5-nitroantranilat + H2O 5-nitrosalicilat + NH3
Ovaj enzim katalizuje inicijalni korak u biodegradaciji 5-nitroantranilne kiselina u zemljišnoj bakteriji Bradyrhizobium, vrsta JS329.
Reference uredi
- ↑ Qu, Y. and Spain, J.C. (2010). „Biodegradation of 5-nitroanthranilic acid by Bradyrhizobium sp. strain JS329”. Appl. Environ. Microbiol. 76: 1417-1422. PMID 20081004.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.