23S rRNK (pseudouridin1915-N3)-metiltransferaza
23S rRNK (pseudouridin1915-N3)-metiltransferaza (EC 2.1.1.177, YbeA, RlmH, pseudouridinska metiltransferaza, m3Psi metiltransferaza, Psi1915-specifična metiltransferaza, metiltransferaza H velike podjedinice rRNK) je enzim sa sistematskim imenom S-adenozil-L-metionin:23S rRNK (pseudouridin1915-N3)-metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 23S rRNK (pseudouridin1915-N3)-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.177 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- S-adenozil-L-metionin + pseudouridin1915 u 23S rRNK S-adenozil-L-homocistein + N3-metilpseudouridin1915 u 23S rRNK
YbeA ne metiliše uridin u poziciji 1915.
Reference uredi
- ↑ Ero, R., Peil, L., Liiv, A. and Remme, J. (2008). „Identification of pseudouridine methyltransferase in Escherichia coli”. RNA 14: 2223-2233. PMID 18755836.
- ↑ Purta, E., Kaminska, K.H., Kasprzak, J.M., Bujnicki, J.M. and Douthwaite, S. (2008). „YbeA is the m3Ψ methyltransferase RlmH that targets nucleotide 1915 in 23S rRNA”. RNA 14: 2234-2244. PMID 18755835.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.