16S rRNK (citozin1407-C5)-metiltransferaza
16S rRNK (citozin1407-C5)-metiltransferaza (EC 2.1.1.178, RNK m5C metiltransferaza YebU, RsmF, YebU) je enzim sa sistematskim imenom S-adenozil-L-metionin:16S rRNK (citozin1407-C5)-metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
16S rRNK (citozin1407-C5)-metiltransferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.1.1.178 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- S-adenozil-L-metionin + citozin1407 u 16S rRNK S-adenozil-L-homocistein + 5-metilcitozin1407 u 16S rRNK
Ovaj enzim specifično metiliše citozin1407 u C5 poziciji unutar 16S rRNK.
Reference uredi
- ↑ Andersen, N.M. and Douthwaite, S. (2006). „YebU is a m5C methyltransferase specific for 16 S rRNA nucleotide 1407”. J. Mol. Biol. 359: 777-786. PMID 16678201.
- ↑ Hallberg, B.M., Ericsson, U.B., Johnson, K.A., Andersen, N.M., Douthwaite, S., Nordlund, P., Beuscher, A.E., 4th and Erlandsen, H. (2006). „The structure of the RNA m5C methyltransferase YebU from Escherichia coli reveals a C-terminal RNA-recruiting PUA domain”. J. Mol. Biol. 360: 774-787. PMID 16793063.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.