1-Aminociklopropan-1-karboksilatna deaminaza
1-Aminociklopropan-1-karboksilatna deaminaza (EC 3.5.99.7, 1-aminociklopropan-1-karboksilatna endolijaza (deaminacija)) je enzim sa sistematskim imenom 1-aminociklopropan-1-karboksilat aminohidrolaza (izomerizacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 1-Aminociklopropan-1-karboksilatna deaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.99.7 | ||||||||
| CAS broj | 69553-48-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- 1-aminociklopropan-1-karboksilat + H2O 2-oksobutanoat + NH3
Ovaj piridoksal 5'-fosfatni enzim je korišćen da se sazrevanje voća učini zavisnim od eksterno dodatog etilena, jer on uklanja supstrat za endogeno formiranje etilena.
Reference uredi
- ↑ Honma, M. and Shimomura, T. (1978). „Metabolism of 1-aminocyclopropane-1-carboxylic acid”. Agric. Biol. Chem. 42: 1825-1831.
- ↑ Yao, M., Ose, T., Sugimoto, H., Horiuchi, A., Nakagawa, A., Wakatsuki, S., Yokoi, D., Murakami, T., Honma, M. and Tanaka, I. (2000). „Crystal structure of 1-aminocyclopropane-1-carboxylate deaminase from Hansenula saturnus”. J. Biol. Chem. 275: 34557-34565. PMID 10938279.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.