(Citohrom c)-lizin N-metiltransferaza
(Citohrom c)-lizin N-metiltransferaza (EC 2.1.1.59, citohrom c (lizin) metiltransferaza, citohrom c metiltransferaza, citohrom c-specifična proteinska metilaza III, citohrom c-specifična protein-lizinska metiltransferaza, S-adenozil-L-metionin:(citohrom c)-L-lizin 6-N-metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:(citohrom c)-L-lizin N6-metiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
(Citohrom c)-lizin N-metiltransferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.1.1.59 | ||||||||
CAS broj | 82047-78-7 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- S-adenozil-L-metionin + citohrom c-L-lizin S-adenozil-L-homocistein + [citohrom c]-N6-metil-L-lizin
Ovaj enzim pripada grupi metilacinih proteina, cf. EC 2.1.1.43, histon-lizin N-metiltransferaza i EC 2.1.1.60, kalmodulin-lizin N-metiltransferaza.
Reference uredi
- ↑ Durban, E., Nochumson, S., Kim, S. and Paik, W.K. (1978). „Cytochrome c-specific protein-lysine methyltransferase from Neurospora crassa. Purification, characterization, and substrate requirements”. J. Biol. Chem. 253: 1427-1435. PMID 203592.
- ↑ Nochumson, S., Durban, E., Sangduk, K. and Paik, W.K. (1977). „Cytochrome c-specific protein methylase III from Neurospora crassa”. Biochem. J. 165: 11-18. PMID 196592.
- ↑ Valentine, J. and Pettigrew, G.W. (1982). „A cytochrome c methyltransferase from Crithidia oncopelti”. Biochem. J. 201: 329-338. PMID 6282265.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.