(R)-limonenska sintaza
(Preusmjereno sa stranice (+)-limonene synthase)
(R)-limonenska sintaza (EC 4.2.3.20, (+)-limonen sintaza, geranildifosfat difosfatna lijaza (formira (+)-(R)-limonen), geranil-difosfatna difosfat-lijaza (ciklizacija, formira (+)-(4R)-limonen)) je enzim sa sistematskim imenom geranil-difosfat difosfat-lijaza (ciklizacija, formira (R)-limonen).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| (R)-limonenska sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.3.20 | ||||||||
| CAS broj | 155807-65-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- geranil difosfat (R)-limonen + difosfat
Ovaj enzim posreduje prvi korak u biosintezi karvona.
Reference uredi
- ↑ Bouwmeester, H.J., Gershenzon, J., Konings, M.C.J.M. and Croteau, R. (1998). „Biosynthesis of the monoterpenes limonene and carvone in the fruit of caraway. I. Demonstration of enzyme activities and their changes with development”. Plant Physiol. 117: 901-912. PMID 9662532.
- ↑ Lücker, J., El Tamer, M.K., Schwab, W., Verstappen, F.W., van der Plas, L.H., Bouwmeester, H.J. and Verhoeven, H.A. (2000). „Monoterpene biosynthesis in lemon (Citrus limon). cDNA isolation and functional analysis of four monoterpene synthases”. Eur. J. Biochem. 269: 3160-3171. PMID 12084056.
- ↑ Maruyama, T., Ito, M., Kiuchi, F. and Honda, G. (2001). „Molecular cloning, functional expression and characterization of d-limonene synthase from Schizonepeta tenuifolia”. Biol. Pharm. Bull. 24: 373-377. PMID 11305598.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.