(S)-2-metilmalatna dehidrataza
(Preusmjereno sa stranice (+)-citramalatna hidrolijaza)
(S)-2-metilmalatna dehidrataza (EC 4.2.1.34, mesakonatna hidrataza, (+)-citramalatna hidrolijaza, L-citramalatna hidrolaza, citramalatna dehidrataza, (+)-citramalatna hidrolijaza, mesakonatna mesakonaza, mesakonaza, (S)-2-metilmalatna hidrolijaza) je enzim sa sistematskim imenom (S)-2-metilmalat hidrolijaza (formira 2-metilfumarat).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| (S)-2-metilmalatna dehidrataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.1.34 | ||||||||
| CAS broj | 9027-94-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- (S)-2-metilmalat 2-metilfumarat + H2O
Ovaj enzhim takiđe hidratiše fumarat do (S)-malata.
Reference uredi
- ↑ Blair, A.H. and Barker, H.A. (1966). „Assay and purification of (+)-citramalate hydro-lyase components from Clostridium tetanomorphum”. J. Biol. Chem. 241: 400-408. PMID 5903732.
- ↑ Wang, C.C. and Barker, H.A. (1969). „Purification and properties of L-citramalate hydrolyase”. J. Biol. Chem. 244: 2516-2526. PMID 5769987.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.