(+)-Kar-3-enska sintaza

(+)-Kar-3-enska sintaza (EC 4.2.3.107, 3-karenska ciklaza, 3-karenska sintaza, 3CAR, (+)-3-karenska sintaza) je enzim sa sistematskim imenom geranil-difosfat difosfat-lijaza (ciklizacija, formira (+)-car-3-en).[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju

(+)-Kar-3-enska sintaza
Identifikatori
EC broj 4.2.3.107
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum
geranil difosfat (+)-kar-3-en + difosfat

Ovaj enzim reaguje sa (3S)-linalil difosfatom dva puta brže od geranil difosfata.

Reference uredi

  1. Savage, T.J. and Croteau, R. (1993). „Biosynthesis of monoterpenes: regio- and stereochemistry of (+)-3-carene biosynthesis”. Arch. Biochem. Biophys. 305: 581-587. PMID 8373196. 
  2. Savage, T.J., Ichii, H., Hume, S.D., Little, D.B. and Croteau, R. (1995). „Monoterpene synthases from gymnosperms and angiosperms: stereospecificity and inactivation by cysteinyl- and arginyl-directed modifying reagents”. Arch. Biochem. Biophys. 320: 257-265. PMID 7625832. 
  3. Savage, T.J., Hatch, M.W. and Croteau, R. (1994). „Monoterpene synthases of Pinus contorta and related conifers. A new class of terpenoid cyclase”. J. Biol. Chem. 269: 4012-4020. PMID 8307957. 
  4. Faldt, J., Martin, D., Miller, B., Rawat, S. and Bohlmann, J. (2003). „Traumatic resin defense in Norway spruce (Picea abies): methyl jasmonate-induced terpene synthase gene expression, and cDNA cloning and functional characterization of (+)-3-carene synthase”. Plant Mol. Biol. 51: 119-133. PMID 12602896. 
  5. Hamberger, B., Hall, D., Yuen, M., Oddy, C., Hamberger, B., Keeling, C.I., Ritland, C., Ritland, K. and Bohlmann, J. (2009). „Targeted isolation, sequence assembly and characterization of two white spruce (Picea glauca) BAC clones for terpenoid synthase and cytochrome P450 genes involved in conifer defence reveal insights into a conifer genome”. BMC Plant Biol. 9: #106-106. PMID 19656416. 
  6. Hall, D.E., Robert, J.A., Keeling, C.I., Domanski, D., Quesada, A.L., Jancsik, S., Kuzyk, M.A., Hamberger, B., Borchers, C.H. and Bohlmann, J. (2011). „An integrated genomic, proteomic and biochemical analysis of (+)-3-carene biosynthesis in Sitka spruce (Picea sitchensis) genotypes that are resistant or susceptible to white pine weevil”. Plant J. 65: 936-948. PMID 21323772. 

Literatura uredi

Spoljašnje veze uredi