(+)-Delta-selinenska sintaza

(+)-Delta-selinenska sintaza (EC 4.2.3.76, (+)-delta-selinene synthase) je enzim sa sistematskim imenom (2E,6E)-farnezil-difosfat difosfat-lijaza (formira (+)-delta-selinen).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju

(+)-Delta-selinenska sintaza
Identifikatori
EC broj 4.2.3.76
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum
(2E,6E)-farnezil difosfat (+)-delta-selinen + difosfat

Inicijalna ciklizacija daje germakren C vezan za enzim.

Reference uredi

  1. Steele, C.L., Crock, J., Bohlmann, J. and Croteau, R. (1998). „Sesquiterpene synthases from grand fir (Abies grandis). Comparison of constitutive and wound-induced activities, and cDNA isolation, characterization, and bacterial expression of δ-selinene synthase and γ-humulene synthase”. J. Biol. Chem. 273: 2078-2089. PMID 9442047. 
  2. Little, D.B. and Croteau, R.B. (2002). „Alteration of product formation by directed mutagenesis and truncation of the multiple-product sesquiterpene synthases δ-selinene synthase and γ-humulene synthase”. Arch. Biochem. Biophys. 402: 120-135. PMID 12051690. 

Literatura uredi

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