UDP-šećerna difosfataza
UDP-šećerna difosfataza (EC 3.6.1.45, nukleoziddifosfat-šećerna pirofosfataza, nukleoziddifosfat-šećerna difosfataza, UDP-šećerna hidrolaza, UDP-šećerna pirofosfataza) je enzim sa sistematskim imenom UDP-šećer šećerfosfohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| UDP-šećerna difosfataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.6.1.45 | ||||||||
| CAS broj | 55354-38-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- UDP-šećer + H2O UMP + alfa-D-aldoza 1-fosfat
Dvovalentni katjon je neophodan za dejstvo.
Reference uredi
- ↑ Garrett, A.R., Johnson, L.A., Beacham, I.R. (1989). „Isolation, molecular characterization and expression of the ushB gene of Salmonella typhimurium which encodes a membrane bound UDP-sugar hydrolase”. Mol. Microbiol. 3: 177-186. PMID 2548058.
- ↑ Glaser, L., Melo, A., Paul, R. (1987). „Uridine diphosphate sugar hydrolase. Purification of enzyme and protein inhibitor”. J. Biol. Chem. 242: 1944-1954. PMID 5337593.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.