Tropomiozin kinaza
Tropomiozin kinaza (EC 2.7.11.28, tropomiozinska kinaza (fosforilacija), STK) je enzim sa sistematskim imenom ATP:tropomiozin O-fosfotransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Tropomiozin kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.11.28 | ||||||||
| CAS broj | 90804-56-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- ATP + tropomiozin ADP + O-fosfotropomiozin
Ovaj enzim u istoj meri fosforiliše kazein, i u manjoj meri histon i fosvitin.
Reference uredi
- ↑ deBelle, I. and Mak, A.S. (1987). „Isolation and characterization of tropomyosin kinase from chicken embryo”. Biochim. Biophys. Acta 925: 17-26. PMID 3593768.
- ↑ Montgomery, K. and Mak, A.S. (1984). „In vitro phosphorylation of tropomyosin by a kinase from chicken embryo”. J. Biol. Chem. 259: 5555-5560. PMID 6325440.
- ↑ Watson, M.H., Taneja, A.K., Hodges, R.S. and Mak, A.S. (1988). „Phosphorylation of α α- and β β-tropomyosin and synthetic peptide analogues”. Biochemistry 27: 4506-4512. PMID 3166994.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.