Tropinsteraza
Tropinsteraza (EC 3.1.1.10, tropinska esteraza, atropinaza, atropinska esteraza) je enzim sa sistematskim imenom atropin acilhidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Tropinsteraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.1.10 | ||||||||
| CAS broj | 59536-71-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ovaj enzim takođe deluje na kokain i druge tropinske estre.
Reference uredi
- ↑ Glick, D., Glaubach, S. and Moore, D.H. (1942). „Azolesterase activities of electrophoretically separated proteins of serum”. J. Biol. Chem. 144: 525-528.
- ↑ Moog, P. and Krisch, K. (1974). „[The purification and characterization of atropine esterase from rabbit liver microsomes]”. Hoppe-Seyler's Z. Physiol. Chem. 355: 529-542. PMID 4435736.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.